Timepidium bromide
Chemical compound
- A03AB19 (WHO)
- In general: ℞ (Prescription only)
- 3-(di-2-thienylmethylene)-5-methoxy-1,1-dimethylpiperidinium bromide
- 35035-05-3 Y
- 160243
- 140841 N
- 8R9E4766V4
- DTXSID4023672
- Interactive image
- C[N+]1(CC(CC(=C(C2=CC=CS2)C3=CC=CS3)C1)OC)C.[Br-]
InChI
- InChI=1S/C17H22NOS2.BrH/c1-18(2)11-13(10-14(12-18)19-3)17(15-6-4-8-20-15)16-7-5-9-21-16;/h4-9,14H,10-12H2,1-3H3;1H/q+1;/p-1 N
- Key:QTSXMEPZSHLZFF-UHFFFAOYSA-M N
Timepidium bromide (INN) is an anticholinergic. It is used in the symptomatic treatment of visceral spasms.[1] It is also used to relieve pain associated with various gastrointestinal disorders.[2] The quaternary nitrogen prevents it from crossing the blood brain barrier, so it is peripherally acting with no central side effects.
The same compound sans the quaternary methyl group and the methoxy ether is called tipepidine.[3]
References
- ^ "Timepidium bromide: Indication, Dosage, Side Effect, Precaution | MIMS Malaysia". www.mims.com. Retrieved 2021-07-05.
- ^ "Timepidium Bromide Tablets 30mg SAWAI 100 Tablets|Natural Pharmacy". www.mimaki-family-japan.com. Retrieved 2021-07-05.
- ^ Shah R, Verma PK (December 2018). "Therapeutic importance of synthetic thiophene". Chemistry Central Journal. 12 (1): 137. doi:10.1186/s13065-018-0511-5. PMC 6768136. PMID 30564984.
- v
- t
- e
Drugs for functional gastrointestinal disorders (A03)
functional
bowel
disorders
Antimuscarinics |
| ||||
---|---|---|---|---|---|
Phosphodiesterase inhibitors | |||||
Acting on serotonin receptors |
| ||||
Other |
and derivatives
(antimuscarinics)
- Tertiary amines: Atropine
- Hyoscyamine
- Quaternary ammonium compounds:
- Cimetropium bromide
- Fentonium bromide
- Methylatropine
- Primarily dopamine antagonists
- 5-HT4 agonists
- Acotiamide
- Ilebopride
- Mosapride
This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e