Chloral betaine
Chemical compound
- None
- US: Schedule IV
- 2,2,2-Trichloro-1,1-ethanediol : (trimethylammonio)acetate (1:1)
- 2218-68-0
- 16676
- DB01494
- 15813
- 8680278NRH
- DTXSID20176716
- Interactive image
- C[N+](C)(C)CC(=O)[O-].C(C(Cl)(Cl)Cl)(O)O
InChI
- InChI=1S/C5H11NO2.C2H3Cl3O2/c1-6(2,3)4-5(7)8;3-2(4,5)1(6)7/h4H2,1-3H3;1,6-7H
- Key:ONAOIDNSINNZOA-UHFFFAOYSA-N
Chloral betaine (USAN, BAN) (brand names Beta-Chlor, Somilan), also known as cloral betaine (INN), is a sedative-hypnotic drug.[1][2][3][4] It was introduced by Mead Johnson in the United States in 1963.[5] It is a betaine complex of trimethylglycine with chloral hydrate, which acts as an extended-acting formulation of chloral hydrate which is then metabolized into trichloroethanol, which is responsible for most or all of its effects.[3][4][6]
See also
References
- ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 1231–. ISBN 978-1-4757-2085-3.
- ^ Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 72–. ISBN 978-94-011-4439-1.
- ^ a b Bassuk EL, Schoonover SC, Gelenberg AJ (6 December 2012). The Practitioner's Guide to Psychoactive Drugs. Springer Science & Business Media. pp. 208–. ISBN 978-1-4615-8049-2.
- ^ a b Lowry W (6 December 2012). Forensic Toxicology: Controlled Substances and Dangerous Drugs. Springer Science & Business Media. pp. 157–. ISBN 978-1-4684-3444-6.
- ^ William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 944–. ISBN 978-0-8155-1856-3.
- ^ Maxwell GM (6 December 2012). Principles of Paediatric Pharmacology. Springer Science & Business Media. pp. 124–. ISBN 978-1-4684-7544-9.
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