Alfadolone
Chemical compound
- none
- (3R,5S,9S,14S)-3-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one
- 14107-37-0 N
- 71680
- 7974182 Y
- OE1C96974E
- ChEMBL2104019 N
- DTXSID501016382
- Interactive image
- O=C2[C@H]3[C@H]([C@@H]1CC[C@H](C(=O)CO)[C@@]1(C)C2)CC[C@H]4C[C@H](O)CC[C@]34C
InChI
- InChI=1S/C21H32O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h12-16,19,22-23H,3-11H2,1-2H3/t12-,13+,14-,15-,16+,19+,20-,21-/m0/s1 Y
- Key:XWYBFXIUISNTQG-VKMGZQQJSA-N Y
Alfadolone (INN), or alphadolone is a neuroactive steroid and general anesthetic.[1] Along with alfaxolone, as alfadolone acetate, it is one of the components of the anesthetic drug mixture althesin.[1]
Chemistry
See also
- Ganaxolone
- Hydroxydione
- Minaxolone
- Pregnanolone
- Renanolone
References
- ^ a b Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1094–. ISBN 978-0-412-46630-4.
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- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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