Propamidine
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Preferred IUPAC name 4,4′-[Propane-1,3-diylbis(oxy)]di(benzene-1-carboximidamide) | |
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ECHA InfoCard | 100.002.905 |
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Properties | |
Chemical formula | C17H20N4O2 |
Molar mass | 312.373 g·mol−1 |
Pharmacology | |
D08AC03 (WHO) S01AX15 (WHO) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Propamidine is an antiseptic and disinfectant.
Propamidine isethionate, the salt of propamidine with isethionic acid, is used in the treatment of Acanthamoeba infection.[1]
Propamidine is a member of the aromatic diamidine group of compounds which possess bacteriostatic properties against a wide range of organisms. These diamidines exert antibacterial action against pyrogenic cocci, antibiotic resistant staphylococci and some Gram-negative bacilli, the activity of the diamidines being retained in the presence of organic matter such as tissue fluids, pus and serum.[2]
References
- ^ Perrine D, Chenu JP, Georges P, Lancelot JC, Saturnino C, Robba M (February 1995). "Amoebicidal efficiencies of various diamidines against two strains of Acanthamoeba polyphaga". Antimicrob. Agents Chemother. 39 (2): 339–42. doi:10.1128/aac.39.2.339. PMC 162538. PMID 7726493.
- ^ "Brolene Eye Drops - Summary of Product Characteristics (SmPC) - (eMC)". www.medicines.org.uk. Retrieved 2018-11-23.
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- Dibrompropamidine
- Chlorhexidine#
- Propamidine
- Hexamidine
- Polihexanide
- Mercuric amidochloride
- Phenylmercuric borate
- Mercuric chloride
- Merbromin
- Nitromersol
- Thiomersal
- Mercuric iodide
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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