Butanilicaine
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Names | |
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IUPAC name N2-Butyl-N1-(2-chloro-6-methylphenyl)glycinamide | |
Systematic IUPAC name 2-(Butylamino)-N-(2-chloro-6-methylphenyl)acetamide | |
Identifiers | |
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ChEBI |
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InChI
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Properties | |
Chemical formula | C13H19ClN2O |
Molar mass | 254.75576 |
Pharmacology | |
N01BB05 (WHO) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Butanilicaine is a local anesthetic. It is also known by the name Hostacaine.
Synthesis
Amide formation by the combination of 2-chloro-6-methylaniline (1) and chloroacetyl chloride (2) gives the intermediate (3), which is used to alkylate N-butylamine (4) to yield butanilicaine.[1][2][3]
References
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Aminobenzoic | |
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Benzoic | |
ArCO2- (not para-amino or Ph) |
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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