Bephenium hydroxynaphthoate
Chemical compound
- Undefined
administration
- P02CX02 (WHO)
- N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxynaphthalene-2-carboxylate
- 3818-50-6 N
7181-73-9 (bephenium)
- 54678490
- 18524 Y
- 47RU9546DX
- ChEMBL1673148 N
- DTXSID8022662
- Interactive image
- C[N+](C)(CCOc1ccccc1)Cc2ccccc2.c1ccc2cc(c(cc2c1)C(=O)[O-])O
InChI
- InChI=1S/C17H22NO.C11H8O3/c1-18(2,15-16-9-5-3-6-10-16)13-14-19-17-11-7-4-8-12-17;12-10-6-8-4-2-1-3-7(8)5-9(10)11(13)14/h3-12H,13-15H2,1-2H3;1-6,12H,(H,13,14)/q+1;/p-1 N
- Key:PMPQCPQAHTXCDK-UHFFFAOYSA-M N
Bephenium hydroxynaphthoate (INN, trade names Alcopara, Alcopar, Befenium, Debefenium, Francin, Nemex) is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.[1][2] It is formulated as a salt between the active pharmaceutical ingredient, bephenium, and 3-hydroxy-2-naphthoic acid.[citation needed]
Bephenium is not FDA-approved and is not available in the United States.[3]
References
- ^ Sweetman S, ed. (2009). Martindale: The complete drug reference (36th ed.). London: Pharmaceutical Press. p. 143. ISBN 978-0-85369-840-1.
- ^ Jayewardene G, Ismail MM, Wijayaratnam Y (July 1960). "Bephenium hydroxynaphthoate in treatment of ascariasis". Br Med J. 2 (5194): 268–71. doi:10.1136/bmj.2.5194.268. PMC 2097409. PMID 14406934.
- ^ Pham PA (March 19, 2009). "Bephenium hydroxynaphthoate". Point-of-Care Information Technology ABX Guide. Johns Hopkins University. Retrieved on March 25, 2011.
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Antitrematodals (schistosomicides) |
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Anticestodals (taeniacides) |
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macrofilaricides)
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Glutamate-gated chloride channel, GABA receptor | |
NMDA |
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Other/unknown |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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